HTS FOR FADD KINASE INHIBITORS USING MOLECULAR IMAGING


Year of Award:
2008
Award Type:
R21
Project Number:
CA131859
RFA Number:
RFA-CA-07-033
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
REHEMTULLA, ALNAWAZ
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF MICHIGAN
Using differential expression profiling, quantitative two-dimensional (2-D) gel electrophoresis and data mining we recently identified a new prognostic biomarker, Fas-associated death domain (FADD), which is overexpressed in a number of human malignancies