DEVELOPMENT AND APPLICATION OF TECHNOLOGY PLATFORM FOR IDENTIFICATION OF THE HIST


Year of Award:
2008
Award Type:
R43
Project Number:
CA132680
RFA Number:
RFA-CA-07-041
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
CHAN, DOUG
Other PI or Project Leader:
N/A
Institution:
PROTECH LABORATORIES, INC.
Post-translational modifications of the N-terminal tail of histones play important roles in epigenetic regulation. The histone code hypothesis proposes that modifications of histone tails create combinatorial binding sites to recruit enzymes for transcrip