Year of Award:
2008
Status:
Complete
Award Type:
R43
Project Number:
CA132680
RFA Number:
RFA-CA-07-041
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
CHAN, DOUG
Other PI or Project Leader:
N/A
Institution:
PROTECH LABORATORIES, INC.
External Link:
http://projectreporter.nih.gov/project_info_details.cfm?aid=7434194
Post-translational modifications of the N-terminal tail of histones play important roles in epigenetic regulation. The histone code hypothesis proposes that modifications of histone tails create combinatorial binding sites to recruit enzymes for transcrip