USING SYNTHETIC DOSAGE LETHALITY TO SCREEN FOR NOVEL ANTI-TUMOR TARGETS


Year of Award:
2007
Award Type:
R33
Project Number:
CA125520
RFA Number:
RFA-CA-07-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ROTHSTEIN, RODNEY J.
Other PI or Project Leader:
N/A
Institution:
COLUMBIA UNIVERSITY HEALTH SCIENCES
The significant challenge in cancer therapy is to selectively kill cancer cells while not harming normal cells. Novel therapeutic targets are needed to develop new cancer drugs that will achieve this goal. Cancer cells often increase expression of specifi