IDENTIFICATION OF AREAS OF OXIDATIVE DAMAGE IN HUMAN GENOMIC DNA


Year of Award:
2007
Award Type:
R21
Project Number:
CA125337
RFA Number:
RFA-CA-07-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KAUFMAN, DAVID G.
Other PI or Project Leader:
N/A
Institution:
UNIV OF NORTH CAROLINA CHAPEL HILL
While considerable attention has been given to mapping sites of carcinogen-induced mutations in a number of cancer related genes, less is known about the distribution of the original DMA damage that might have given rise to mutagenic lesions. The goal of