BAC-FISH ASSAYS FOR SENSITIVE KARYOTYPING OF CANCER CELLS


Year of Award:
2007
Award Type:
R21
Project Number:
CA123370
RFA Number:
RFA-CA-07-015
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WEIER, HEINZ-ULRICH G.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB
The detailed cytogenetic analyses of human tumors and cancer tissues, in particular, have revealed the presence of structural chromosome abnormalities in most of cases. The underlying changes are often specific for the type of tumor or cancer and the cell