AN RNA SENSOR FOR DETECTION OF CIRCULATING TUMOR CELLS


Year of Award:
2006
Award Type:
R33
Project Number:
CA118591
RFA Number:
RFA-CA-06-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
CLAWSON, GARY A.
Other PI or Project Leader:
N/A
Institution:
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
This proposal seeks to develop an RNA Sensor to be employed for detection of circulating tumor cells. RNA detection is based upon an hybridization 'sandwich'. Two target RNAs have been chosen for clinically important cancers (prostate, breast, and melanom