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NOVEL PROBE FOR QUANTITATIVE IMAGING OF GENE EXPRESSION


Year of Award:
2006
Status:
Complete
Award Type:
R21
Project Number:
CA116102
RFA Number:
RFA-CA-06-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TSOURKAS, ANDREW
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF PENNSYLVANIA
We propose to develop a molecular imaging probe that will provide quantitative information on theexpression level of mRNA with spatial and temporal resolution. Specifically, an oligonucleotide-based probewill be designed to form a stem-loop structure and