MICROARRAY PLATFORM FOR PROFILING CANCER PROTEASES


Year of Award:
2006
Award Type:
R33
Project Number:
CA118696
RFA Number:
RFA-CA-06-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
CRAVATT, BENJAMIN F
Other PI or Project Leader:
N/A
Institution:
SCRIPPS RESEARCH INSTITUTE
Proteases are suspected to play major roles in cancer, including the activation/inactivation of growth factors and the degradation of extracellular matrix components to promote cancer cell migration and invasion. Consistent with this premise, transcript a