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DXMS-FACILITATED MEMBRANE PROTEIN CONSTRUCT DESIGN/CANCER


Year of Award:
2006
Status:
Complete
Award Type:
R21
Project Number:
CA118595
RFA Number:
RFA-CA-06-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WOODS, VIRGIL L
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA SAN DIEGO
Many cancer-implicated proteins are integral membrane proteins (IMPs). There is a pressing need for improved methods for the production of IMP constructs for use in high-resolution structure determination efforts. Three years ago, we completed a fifteen-