TARGETING MIRNA IN BRAIN TUMORS.


Year of Award:
2005
Award Type:
R21
Project Number:
CA116141
RFA Number:
RFA-CA-05-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KRICHEVSKY, ANNA M.
Other PI or Project Leader:
N/A
Institution:
BRIGHAM AND WOMEN'S HOSPITAL
MicroRNAs (miRNAs) are a recently discovered class of small 20-22 nucleotide non-coding RNA molecules that have been shown to regulate target gene expression in various organisms. By targeting the mRNA of protein-coding genes for either cleavage or repres