Year of Award:
2005
Status:
Complete
Award Type:
R33
Project Number:
CA112885
RFA Number:
RFA-CA-05-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MALKHOSYAN, SERGEI R
Other PI or Project Leader:
N/A
Institution:
SANFORD-BURNHAM MEDICAL RESEARCH INSTIT
External Link:
http://projectreporter.nih.gov/project_info_details.cfm?aid=6887078
Distortion of the cell genome characterizes neoplastic transformation. Genetic alterations that occur in tumor cells lead to activation of positive regulators of cell growth or survival and inactivation of factors that suppress these processes. A particul