GENOME INSTABILITY IN CELLS AND TISSUES OF THE ZEBRAFISH


Year of Award:
2005
Award Type:
R21
Project Number:
CA116210
RFA Number:
RFA-CA-05-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SPENCER, FORREST A.
Other PI or Project Leader:
N/A
Institution:
JOHNS HOPKINS UNIVERSITY
Change in genome structure can occur in mitotic and meiotic cell lineages, and this contributes to individual variation, evolution, and disease. It has been argued that stochastic somatic genome instability makes an early and important contribution to the