A NOVEL PROTEOMICS TECHNOLOGY FOR PROTEIN FARNESYLATION


Year of Award:
2004
Award Type:
R21
Project Number:
CA107943
RFA Number:
PAR-01-104
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ZHAO, YINGMING
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF TEXAS SW MED CTR/DALLAS
The identification and characterization of changes in the level of farnesylated proteins in response to the treatment of farnesyltransferase inhibitors (FTIs), a newly introduced family of antitumor agents currently undergoing clinical evaluation, represe