TECHNOLOGY FOR GENOME-WIDE CANCER METHYLATION PROFILING


Year of Award:
2002
Award Type:
R43
Project Number:
CA097505
RFA Number:
PAR-01-105
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
JOHNSON, PAUL H
Other PI or Project Leader:
N/A
Institution:
EPIGENX PHARMACEUTICALS
A high-throughput technology, termed DMS2 (DMS square) for DirectMicroarray-based Screening of Differentially Methylated CpG Sites, has beendeveloped for the discovery of abnormally methylated sites as cancer molecularmarkers. Combining the methylation sp