RAPID ANALYSIS OF CPG METHYLATION CHANGES IN CANCER


Year of Award:
2002
Status:
Complete
Award Type:
R43
Project Number:
CA097483
RFA Number:
PAR-01-105
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
HANNA, MICHELLE M
Other PI or Project Leader:
N/A
Institution:
RIBOMED BIOTECHNOLOGIES, INC.
The objective of this project is the development of a rapid and sensitiveassay system for the detection of CpG methylation in tumors and precancerouscells. Methylation of clustered CpG sequences, called CpG islands, is an earlyand widespread marker of tum