PROTEIN LOCALIZATION: MULTI-APERTURE NEAR-FIELD OPTICS


Year of Award:
2002
Award Type:
R21
Project Number:
CA094354
RFA Number:
PAR-01-104
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LARSON, DALE N
Other PI or Project Leader:
N/A
Institution:
HARVARD UNIVERSITY (MEDICAL SCHOOL)
The objective for this research is to develop a new form of microscopy,Surface Plasmon Enhanced Microscopy (SPEM). SPEM achieves resolution of 35 nmand is intended to be used for localization of multiple proteins in cells anddetermine molecular signatures