Error message

  • Deprecated function: Optional parameter $feed_nid declared before required parameter $context is implicitly treated as a required parameter in include_once() (line 1439 of /local/drupal/imat/includes/bootstrap.inc).
  • Deprecated function: Optional parameter $input declared before required parameter $form_state is implicitly treated as a required parameter in require_once() (line 12 of /local/drupal/imat/sites/all/modules/media/media.module).
×

PROTEIN KNOCKOUT TECHNOLOGY/MOLECULAR ANALYSIS OF CANCER


Year of Award:
2002
Status:
Complete
Award Type:
R33
Project Number:
CA092792
RFA Number:
PAR-99-102
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ZHOU, PENGBO
Other PI or Project Leader:
N/A
Institution:
WEILL MEDICAL COLLEGE OF CORNELL UNIV
The ubiquitin-proteasome pathway is a major cellular proteolysis machinery that selectively targets cellular proteins for degradation. Protein knockout, a new technology we recently developed, harnesses the specificity of the ubiquitin proteolytic system