PAP: A TECHNOLOGY PLATFORM


Year of Award:
2002
Award Type:
R21
Project Number:
CA094334
RFA Number:
PAR-01-104
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SOMMER, STEVE SEEV
Other PI or Project Leader:
N/A
Institution:
CITY OF HOPE/BECKMAN RESEARCH INSTITUTE
Pyrophosphorolysis activated polymerization (PAP) offers a novel approach forretrieving multiple types of information from nucleic acids. The exceptionalspecificity of PAP derives from an inactive dideoxy terminated oligonucleotide(P*). P* is activated by