OBLIQUELY DEPOSITED SUBSTRATES FOR DETECTION OF RAS


Year of Award:
2002
Status:
Complete
Award Type:
R43
Project Number:
CA096052
RFA Number:
PAR-01-105
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ISRAEL, BARBARA A.
Other PI or Project Leader:
N/A
Institution:
PLATYPUS TECHNOLOGIES, LLC
Key cell signaling molecules, such as Ras, play a central role in carcinogenesis and are the targets for a new generation of drugs that inhibit protein kinases. The ability to measure the activation status of molecules along an entire pathway is of increa