MRI AGENTS SENSITIVE TO BIOLOGICAL INDICATORS OF NEOPLAS


Year of Award:
2002
Award Type:
R33
Project Number:
CA084697
RFA Number:
PAR-98-067
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SHERRY, A. DEAN
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF TEXAS DALLAS
Rapidly dividing neoplastic cells characteristically have high metabolic rates, are O2 limited, and generate excess acid. Thus, physiological indices such as PO2, pH, and excess lactate are often targeted for detection and quantification as an index of tu