METHOD FOR DETECTING CHRONIC MYELOGENOUS LEUKEMIA CELLS


Year of Award:
2002
Award Type:
R43
Project Number:
CA097447
RFA Number:
PAR-01-105
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TRNOVSKY, JAN
Other PI or Project Leader:
N/A
Institution:
ONE CELL SYSTEMS, INC
Chronic myelogenous leukemia (CML) is characterized by a t(9;22) chromosomal translocation, which results in a fusion gene whose protein product shows enhanced tyrosine kinase activity. This fusion protein is a target in a new promising treatment using a