FLUORESCENT TAGS TARGETED ON CELL SURFACE CARBOHYDRATES


Year of Award:
2002
Award Type:
R33
Project Number:
CA088343
RFA Number:
PAR-99-100
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WANG, BINGHE
Other PI or Project Leader:
N/A
Institution:
NORTH CAROLINA STATE UNIVERSITY RALEIGH
Malignant transformation is often associated with alteration of cell surface carbohydrates. The expression or over-expression of certain carbohydrates, such as sialyl Lewis X (sLex), sialyl Lewis a (sLea), Lewis X (Lex) and Lewis Y (Ley), has been correla