TARGET IDENTIFICATION VIA HAPLO INSUFFICIENCY PROFILING


Year of Award:
2001
Award Type:
R33
Project Number:
CA091342
RFA Number:
PAR-99-102
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
DAVIS, RONALD WAYNE
Other PI or Project Leader:
N/A
Institution:
STANFORD UNIVERSITY
We have developed a genomic approach to target identification in yeast that may be broadly applicable to human therapeutics. This approach is based on our observation that drug targets can be identified by their ability to confer sensitivity to a cell whe