MOLECULAR CLONING OF HLA CLASS II TUMOR ANTIGENS


Year of Award:
2001
Award Type:
R33
Project Number:
CA088198
RFA Number:
PAR-99-100
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
HERLYN, DOROTHEE M
Other PI or Project Leader:
N/A
Institution:
WISTAR INSTITUTE
Our major goal is to develop a novel technology to identify HLA class II tumor antigens using a unique cloning approach in filamentous phages which has not been applied to the cloning of class II antigens in the past. This approach has numerous potential