CANCER CLASSIFICATION BASED ON MRNA ISOFORMS


Year of Award:
2001
Award Type:
R33
Project Number:
CA088351
RFA Number:
PAR-99-100
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
FU, XIANG-DONG
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA SAN DIEGO
Messenger RNA precursors are often processed through alternative splicing into multiple mRNA isoforms, which in many cases encode proteins with distinct functions. It is estimated that as many as 30 percent of genes in humans exhibit alternative splicing