AUTOMATED MEASUREMENT OF RAS & RHO ACTIVATION IN CANCER


Year of Award:
2001
Award Type:
R33
Project Number:
CA089828
RFA Number:
PAR-99-102
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
BOSS, GERRY R
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA SAN DIEGO
Ras, the product of the ras protoncogene, relays mitogenic signals from growth factor receptors and plays a prominent role in human carcinogenesis. Rho, a member of the greater Ras family, is necessary for Ras-induced transformation and plays an essentia