Year of Award:
Molecular & Cellular Analysis Technologies
HUANG, TIM H.-M.
Other PI or Project Leader:
UNIVERSITY OF MISSOURI-COLUMBIA
Aberrant DNA methylation frequently occurs in CpG islands, which are 0.2 to 2-kb GC-rich sequences located in the 5 ends of approximately 60 percent of all genes, in neoplasia. This type of epigenetic mutation is associated with the silencing of tumor sup