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SIGMA 1 RECEPTOR PROBES FOR IMAGING TUMOR PROLIFERATION


Year of Award:
1999
Status:
Complete
Award Type:
R41
Project Number:
CA081825
RFA Number:
PAR-98-066
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MACH, ROBERT H
Other PI or Project Leader:
N/A
Institution:
ANASAZI BIOMEDICAL RESEARCH, INC.
The goal of this STTR application is to develop 123I- and 99Tc-labeled labeled sigma-1 (sigma1) receptor imaging agents for Single Photon Emission Computed Tomography (SPECT) studies of solid tumors. This approach is based on the observation that sigma1 r