PHOSPHOINOSITIDE 3-KINASE ASSAYS IN CANCER DIAGNOSIS


Year of Award:
1999
Award Type:
R43
Project Number:
CA081835
RFA Number:
PAR-98-066
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MOSTERT, MICHAEL J
Other PI or Project Leader:
N/A
Institution:
ECHELON BIOSCIENCES, INC.
Phosphoinositide polyphosphates (PtdInsPns), biosynthesized by the interplay of kinases and phosphatases, are key signaling molecules in cellular communication. The lipid kinase, phosphatidylinositol 3-kinase (PI 3-K) has been identified in the control of