GENETIC SELECTION FOR PROTEASES AND THEIR SUBSTRATES


Year of Award:
1999
Status:
Complete
Award Type:
R43
Project Number:
CA081860
RFA Number:
PAR-98-066
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
CHANG, HWAI W
Other PI or Project Leader:
N/A
Institution:
STRATAGENE
The goal of the proposed research is to develop a genetic method, using the eukaryotic host Saccharomyces cerevisiae, to select for protease genes, identify their target recognition sequences, and select for protease inhibitors. This represents a novel a