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EVALUATION OF SEQUENCE SPECIFIC CHANGES IN GENOMIC DNA


Year of Award:
1999
Status:
Complete
Award Type:
R21
Project Number:
CA081732
RFA Number:
PAR-98-067
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
STRAUSS, WILLIAM M
Other PI or Project Leader:
N/A
Institution:
BETH ISRAEL DEACONESS MEDICAL CENTER
We wish to create a technical infrastructure that would serve as a foundation for the study of pathophysiology of DNA CpG methylation in cancer. It has been shown that epigenetic modification of DNA in form of CpG methylation can result in mutations, canc