DEVELOPMENT OF RNA FRIENDLY, HISTOLOGICAL FIXATIVES


Year of Award:
1999
Award Type:
R43
Project Number:
CA083477
RFA Number:
PAR-98-066
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WINZER-SERHAN, URSULA H
Other PI or Project Leader:
N/A
Institution:
AMBION, INC.
There is a critical need for technology that will allow the isolation of high quality RNA from histologically preserved clinical samples. The most commonly used fixative, neural buffered formalin severely compromises subsequent isolation of intact nucleic