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DETECTION OF GENOMIC ALTERATIONS BY MOLECULAR COMBING


Year of Award:
1999
Status:
Complete
Award Type:
R21
Project Number:
CA081721
RFA Number:
PAR-98-067
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
BENSIMON, AARON
Other PI or Project Leader:
N/A
Institution:
PASTEUR INSTITUTE
In a process called 'Molecular Combing' DNA molecules attached at one end to a microscope slide are extended and aligned by a receding air-water interface and left to dry on the surface. The local action of the interface is the same on each of the molecul